what is the effect of asn oligomerization on luvs

quince reviews reddit; how many weeks until thanksgiving; bernhard langer witb tour edge; June 8 2022. which part of the chromatogram represents the asn oligomersaaron jones sunglasses 2021. All Rights Reserved. After overnight incubation, cDNA was purified again and subjected to shrimp alkaline phosphatase (1U, Affymetrix) for 30min at 37C. Ile and Val (the beta-branched residues) induced the three-stranded oligomerization state, whereas Tyr, Lys, Arg, Orn, Glu and Asp induced the two-stranded state. Throughout this work, we report results for the oligomerization of ethylene over Ni-H in a packed bed reactor. The intrinsically disordered protein -synuclein (aSN) forms insoluble aggregates in the brains of Parkinson's disease (PD) patients. After purification with the Agencourt RNAClean XP kit (Beckman Coulter), cDNA biotinylation was performed as follows. Effects Data are represented as mean values + SD (n=2). SCORE: 82 / 120 DAY 2; 23:23 PROGA Click to answer the quiz a HOME THEORY MEDIA MISSION What is 1B shows the release of a fluorescent dye (carboxy-fluorescein) from the lumen of LUVs formed by lipids of different acyl chain lengths in the presence of A1-40. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. Positive and Negative Controls Increasing evidence suggests that the pathogenicity of -synuclein is correlated with the activity of oligomers formed in the early stages of its aggregation process. 3c, d). In one study, naked ASOs were efficiently delivered to the target cell without any delivery vehicle by carefully controlling the plating conditions and the duration of the experiment. Article https://doi.org/10.1007/978-1-0716-0771-8_3. All the expressed genes in each cell type were used as background. Soifer HS, Koch T, Lai J, Hansen B, Hoeg A, Oerum H, et al. Cytotoxicity is mainly associated with the oligomeric species, but we still know little about their assembly and structure. For CAGE-Seq, on the other hand, KD efficiencies were estimated from normalized count per million (CPM) values. The term multimer (/mltmr/) is used in biochemistry for oligomers of proteins that are not covalently bound. Eluted 5 cDNA was then incubated with 6U RNase H (Thermo Fisher Scientific) and 20U RNase ONE ribonuclease for 15min at 37C in order to release the cDNA fragment from the complementary RNA strand. https://doi.org/10.1182/blood-2006-10-053280. Please enable it to take advantage of the complete set of features! Azobenzene-Based Amino Acids for the Photocontrol of Coiled-Coil Peptides. mexican tile sealer home depot   /  after school cleaning jobs near me   / which part of the chromatogram represents the asn oligomers The AsnAsn stacking observed here is similar to the Asn ladder Dont let scams get away with fraud. which part of the chromatogram represents the asn oligomers. Following another purification step, the 3linker was then analogously ligated to the 5linker-ligated cDNA overnight at 16C. Shen W, De Hoyos CL, Migawa MT, Vickers TA, Sun H, Low A, et al. (c-e) Top significantly (P-value <0.05) enriched GO terms for biological processes of commonly DE genes between negative control A and B in LECs and BECs (c, d), and specific DE genes for negative control B (e), using g:ProfileR [19] (relative depth 15). Parkinson's Disease | Labster Virtual Labs During the last decades, the FANTOM (Functional Annotation of the Mammalian Genome) consortium made striking contributions to the discovery and characterization of the lncRNAs by demonstrating, through Cap Analysis of Gene Expression (CAGE-Seq), that the human genome is constitutively transcribed, producing various sense and antisense transcripts [3]. Nat Rev Mol Cell Biol Nature Publishing Group. 2017;543(7644):199204. 1a). Parkinson's Disease - Using an in vitro model of neural degeneration, you will investigate the effects of EGCG, a molecule found in green tea. Once the oligomers are Correspondence to 2004;432(7014):1738. The graph depicts how mutations affect oligomerization and Indeed, this process is expected to 4 be in competition with protein-protein oligomerization, as evidenced by the molecular dynamics simulations and NMR results reported below. In the meantime, tRNA-coated magnetic beads were prepared by adding 3.75g of tRNA (Sigma) to 150g Dynabeads M-270 streptavidin beads (Thermo Fisher Scientific) and incubated for 30min on ice. Myers KJ, Dean NM. Taken together, our study, in conjunction with previously published guidelines and case studies, represents practical advice for precisely studying lncRNA function using ASOs [30,31,32,33]. An official website of the United States government. Subjects. Green dots: DE genes in common between negative control A and B; blue and orange dots: specific to either negative control A or B; red dots: opposite pattern (red). To investigate the potential roles of lncRNAs in vascular biology, we performed antisense oligonucleotide (ASO) knockdowns of lncRNA candidates specifically expressed either in human lymphatic or blood vascular endothelial cells (LECs or BECs) followed by Cap Analysis of Gene Expression (CAGE-Seq). Blood and lymphatic endothelial cell-specific differentiation programs are stringently controlled by the tissue environment. Nucleic Acids Res. 2c, d) and saturation concentration of one of the oligomerizing compounds (C O, 2 *; Fig. Given this enrichment on cell proliferation-related terms, we then analyzed empirically whether negative control B was affecting the ability of LECs to proliferate. The recent technological boost in sequencing approaches unveiled long noncoding RNAs (lncRNAs) as prominent regulatory players of various gene expression levels in a cell-type-specific manner. LETR1 is a lymphatic endothelial-specific lncRNA governing cell proliferation and migration through KLF4 and SEMA3C. Bars represent fold change (FC) values against untransfected cells. M.T., M.I., N.K., and H.S. P-values were calculated using linear regression. For other uses, see, Srpskohrvatski / , "Glossary of basic terms in polymer science (IUPAC Recommendations 1996)", "Heterogeneous catalysts for gas-phase conversion of ethylene to higher olefins", https://en.wikipedia.org/w/index.php?title=Oligomer&oldid=1140991496, Short description is different from Wikidata, Creative Commons Attribution-ShareAlike License 3.0, This page was last edited on 22 February 2023, at 20:21. Increasing evidence suggests that the pathogenicity of -synuclein is correlated with the activity of oligomers formed in the early stages of its aggregation process. 2018;46(12):595066. Groundhog Max Problems, container_memory_working_set_bytes vs container_memory_usage_bytes, National Financial Services Llc Albuquerque, Nm, johnson funeral home anderson sc obituaries. effects of imperialism in china; ars title 13; griffin funeral home monroe, la; jesus said moses wrote genesis. Despite their common developmental origin, they present distinct functional fates in adulthood that rely on robust lineage-specific regulatory programs. BMC Biol BioMed Central. Conformational control in a photoswitchable coiled coil. Vice versa, BEC samples displayed a higher KD trend after comparing to negative control B (Fig. We thank all the members of the FANTOM6 project for fruitful discussions and support throughout the project. (a, b) Correlation of log2FC between differentially expressed (DE) genes in negative control A and B. TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. and J.A.R. 2). New York, NY: Springer US; 2020. p. 4956. Bioconjug Chem. In humans, the A53T mutation induces early onset PD and increases the level of aSN oligomerization and fibrillation propensity, but Thr53 occurs naturally in aSNs of most animals. contributed to the in vitro proliferation analysis and provided comments to the manuscript. The lymphatic vasculature in the 21st century: novel functional roles in homeostasis and disease. Primers are listed in Additionalfile5. However, we also observed that referencing to either negative control A or B led to slight differences in the degree of the KD efficiencies in our CAGE-Seq data compared to qPCR results (Fig. The effect of the extra methylene group on the ligation properties of glutamic (Glu) vs. aspartic (Asp) acid, and glutamine (Gln) vs. asparagine (Asn) amino acids-two pairs of Genes with | log2 fold change (log2FC)|>1 and FDR corrected P-value <0.05 were defined as differentially expressed genes and used for the downstream analysis (Additional file 3). Article The site is secure. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Future studies should also consider alternative delivery methods of the ASOs. 4.7.1). Article Oligomer - Wikipedia lncRNAs are either classified as intergenic (lincRNA), intronic, antisense noncoding transcripts based on the protein-coding genes in their genomic neighborhood, and promoter- or enhancer-derived based on epigenetic markers at their promoters [6,7,8]. Our results showed a thermodynamic stability order (in order of decreasing stability) of: Leu, Met, Ile, Tyr, Phe, Val, Gln, Ala, Trp, Asn, His, Thr, Lys, Ser, Asp, Glu, Arg, Orn, and Gly. The oligomeric state (s) was determined by high-performance size-exclusion chromatography and sedimentation equilibrium analysis in benign medium. WebCompared to the negative control, what is the effect of aSN monomers on LUVs? Our study identifies position 21 as a hinge residue that modulates IAPP amyloidogenicity and cytotoxicity. FOIA a) None, they remain the same b) MeSH What is the effect of aSN oligomerization on LUVs? First, we confirmed, through qPCR, the higher reduction in LECs than BECs of three top downregulated negative control B-specific genes (FARS2, EXTL2, and COLEC12) previously involved in the positive regulation of cell proliferation and physiology [21,22,23,24,25] (Fig. What is the effect of aSN oligomerization on LUVs? a) - Kunduz PLoS Pathog. Once these quality checkpoints were passed, cDNA was first ligated to barcoded 5 linkers (2M) in DNA ligation mighty mix (Takara Biotech) and incubated overnight at 16C. Post author: Post published: June 7, Correlation between the effects of ASYN mutations on oligomerization and inclusion formation. PubMed Based on these results, we therefore decided to exclude negative control B CAGE-Seq libraries from further analyses and only use negative control A to investigate the lncRNA candidate knockdown effects on the transcriptome of either LECs or BECs (Fig. Weba) By binding to the oligomers, it blocks membrane permeabilization b) By binding to LUVs, the membrane repels oligomers c) By entering the LUVs, it expels their content d) By binding to the oligomers, it enhances membrane permeabilization Show transcribed image text Expert Answer 100% (22 ratings) Option A is correct. Anatomy and Physiology. Our dataset comprised 32 CAGE-Seq libraries, as described in Additionalfile2. Google Scholar. 2015;22(1):57. WebWhat Is The Effect Of Asn Oligomerization? edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. WebOligomerization is a chemical process that converts monomers to macromolecular complexes through a finite degree of polymerization. BMC Genomic Data ASN, bad weather effect on the aircraft. https://doi.org/10.1186/s12863-021-00992-1, DOI: https://doi.org/10.1186/s12863-021-00992-1. Moreover, the fact that one negative control caused dramatic changes in one of the tested cell types adds an extra layer of complexity that needs to be carefully evaluated. In the majority, 93% of reads were mapped to the genome, confirming the high quality of the analyzed samples (Additional file 2). Quizlet Checkpoint. In regards to oligomerization state, eight analogs demonstrated the ability to populate exclusively one oligomerization state in benign buffer (0.1 M KCl, 0.05 M K(2)PO(4)(pH 7)). For instance, observed molecular phenotypes must be corroborated by in vitro cellular assays using ASO and orthogonal techniques, such as short interference RNAs (siRNAs) and/or CRISPR interference (CRISPRi). Structural Organization in Animals Solutions. the bible project playlist. Oligomers toxicity seems to be associated with both their ability to https://doi.org/10.1089/ard.1994.4.67. Here, we describe the quality control steps adopted in our analysis pipeline before determining the knockdown effects of three ASOs per lncRNA target on the LEC or BEC transcriptomes. The capped RNA capture was performed by incubating RNase I-treated cDNA with t-RNA-coated magnetic beads for 30min at 37C. Here, we present the early quality control steps adopted in the analysis pipeline prior to determining the transcriptional changes after lncRNA target KD in either LECs or BECs. Thus, these results will aid in the de novo design of new coiled-coil structures, a better understanding of their structure/function relationships and the design of algorithms to predict the presence of coiled-coils within native protein sequences. Yao RW, Wang Y, Chen L-L. Cellular functions of long noncoding RNAs. Hon C-C, Ramilowski JA, Harshbarger J, Bertin N, Rackham OJL, Gough J, et al. The vasculature, composed of blood and lymphatic vessels, undergoes an intricate series of regulatory mechanisms to safeguard the physiological functioning of the organism. Oligomerization Hirakawa S, Hong Y-K, Harvey N, Schacht V, Matsuda K, Libermann T, et al. which part of the chromatogram represents the asn oligomers which part of the chromatogram represents the asn oligomers The effects of different parameters on the growth with oligomerization can be seen in Fig. The functions and unique features of long intergenic non-coding RNA. This site needs JavaScript to work properly. Robinson MD, McCarthy DJ, Smyth GK. Abstract. Moreover, some lncRNA genes do not function through their transcribed RNA molecules but rather through their simple act of transcription [11,12,13,14]. Dont let scams get away with fraud. Keuschnigg J, Karinen S, Auvinen K, Irjala H, Mpindi JP, Kallioniemi O, et al. which part of the chromatogram represents the asn oligomers. In g, P-value: *<0.05, ***<0.001, ****<0.0001, using two-way ANOVA with Dunnets multiple comparisons test against untransfected control. Primary human dermal lymphatic and blood vascular endothelial cells (LECs and BECs) were collected from neonatal foreskin. The FC values of the DE genes were largely overlapping between both negative control ASOs (Fig. WebVerified answer. Hotait M, Nasreddine W, El-Khoury R, Dirani M, Nawfal O, Beydoun A. FARS2 mutations: more than two phenotypes? Oligomerization may be achieved thermally or catalytically; the latter having greater practical importance. In addition to that, the increasing evidence that lncRNAs are involved in various aspects of gene expression regulation emphasizes the relevance of lncRNA classification based on their functions [9, 10]. Increased activation or impaired function of these vascular networks can contribute to the development of severe pathological conditions such as cancer, chronic inflammatory diseases, diseases leading to blindness, metabolic syndrome, atherosclerosis, and neurodegeneration [1, 2]. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. Manage cookies/Do not sell my data we use in the preference centre. https://doi.org/10.1016/j.cell.2020.06.039. In the first step, KD efficiencies of lncRNA candidates determined by qPCR and CAGE-Seq were compared between negative control A and B in the corresponding cell types by performing a linear regression analysis by fitting linear models in R. For qPCR, KD efficiencies were calculated according to the comparative Ct method. Nat Struct Mol Biol Nature Publishing Group. The data can be accessed through the project accession number DRA009940 (https://www.ncbi.nlm.nih.gov/sra/?term=DRA009940). VA RNAI Blocks ASC Oligomerization. The units of an oligomer may be connected by covalent bonds, which may result from bond rearrangement or condensation reactions, or by weaker forces such as hydrogen bonds. The element gallium (Ga) has the second largest liquid range of any element, melting at 29.78 degree celcius and boiling at 2204 degree celcius at Language links are at the top of the page across from the title. LECs were additionally cultured in the presence of 25g/mL cAMP (Sigma); BECs in the presence of endothelial cell growth supplement ECGS/H (PromoCell). In conclusion, the comparison of negative control ASO effects on the targeted cell type transcriptomes highlights the essential need to select a proper control set of multiple negative control ASO based on the investigated cell types. which part of the chromatogram represents the asn oligomers. hazel atlas patterns; haydon school catchment area Permutateur de Menu. oligomer: [noun] a polymer or polymer intermediate containing relatively few structural units. Oligomerization may be achieved thermally or catalytically; the latter having greater practical importance. Photoinduced damage of AsLOV2 domain is accompanied by Nat Biotechnol Nature Publishing Group. 2013;11:59. WebIn this manner, the Syt1 oligomerization lowers the prob- ability of the fusion of the docked vesicle in the absence of the Ca2+trigger (Fig. Both qPCR and CAGE-Seq techniques confirmed that all samples had a KD efficiency higher than 50% regardless of the negative control ASO used (Fig. et al. Oligomerization is a chemical process that converts monomers to macromolecular complexes through a finite degree of polymerization. The processed data are available at the following link: https://fantom.gsc.riken.jp/6/datafiles/. This study complements our previous findings, where we analyzed the functionality of human lncRNAs in vascular biology by performing ASO-mediated knockdown of 2 LEC- and 2 BEC-specific lncRNAs followed by CAGE-Seq [18]. E. coli. 2020;21(1):9323. Nat Rev Genet Nature Publishing Group. P-values were calculated using linear regression. Separation of Coiled-Coil Structures in Lamin A/C Is Required for the Elongation of the Filament. WebEmployee portals. https://doi.org/10.1007/s00335-015-9593-8. Remember that you can check any relevant video on the PC screen. Common, NCA only, and NCB only differential expressed genes of negative control ASOs against untransfected reference control in BECs. At the end of the Parkinsons disease simulation, you will use the purified aSN monomers and oligomers to test the potential effects of Epigallocatechin gallate (EGCG), a polyphenol from green tea. WebNotice: Trying to get property 'display_name' of non-object in /var/www/html/strbrain.com/wp-content/themes/strbrain/single.php on line 12 COLEC12 regulates apoptosis of osteosarcoma through Toll-like receptor 4activated inflammation. Tight control of gene expression at several levels is a crucial prerequisite for maintaining gene plasticity, responsiveness to environmental changes, and ensuring proper development. Nat Commun Nature Publishing Group. Nucleic Acid Ther. 1862;2018(4):7919. In humans, the A53T mutation induces early onset PD and increases the level of aSN oligomerization and fibrillation propensity, but Thr53 occurs naturally in aSNs of most animals. After an additional purification step, cDNA concentration was measured using Quant-iT OliGreen ssDNA reagent and kit (Thermo Fisher Scientific), and the ratio of mRNA/rRNA was analyzed by performing qPCR with ACRB-specific primers and 18S ribosomal cDNA primers on a 7900HT real-time system (Applied Biosystems). 2e, f). Molecular modelling studies, however, showed that packing effects could explain deviations from a direct correlation. The Pro analog prevented coiled-coil formation. 2014;1164:6785. a) Membrane duplication state champs new album 2022; springer spaniel puppies rochester, ny; usbc rules on two handed bowling 2020; iowa high school track and field order of events best sports journalism schools in the world. Sensible use of antisense: how to use oligonucleotides as research tools. The trans-activation region (TAR) and the Rev-response element (RRE) (Rosen et al., 1988; Dayton et al., 1 Solubility Studies: In order to undertand the effect of supercritical ethylene on oligomerization from a molecular point of view, we need to know solubility of the coke molecules and their precursors at the exact conditions we will be doing the oligomerization reactions, so the first part of the project will investigate how the solubility of long oligomers a) Membrane protection b) Membrane formation c) Membrane duplication d) Membrane permeabilization. PubMed Central Ransohoff JD, Wei Y, Khavari PA. https://doi.org/10.1038/nrg2521. Mol. De novo design of a model peptide sequence to examine the effects of single amino acid substitutions in the hydrophobic core on both stability and oligomerization state of coiled-coils. In the first step, raw sequencing reads were subjected to read quality control using standard pipelines [42]. residue controlling islet amyloid polypeptide The https:// ensures that you are connecting to the Science. PubMed The study of protein oligomerization may provide insights into the early protein environment and the evolution of modern proteins. Reimand J, Kull M, Peterson H, Hansen J, Vilo J g. Profiler--a web-based toolset for functional profiling of gene lists from large-scale experiments. You'll get a detailed solution from a subject matter expert that helps you learn core Third, a rigorous evaluation of dose-response and time-course experiments will help determine the best experimental conditions and provide direct comparisons between experiments [30]. Science. Nat Cell Biol Nature Publishing Group. Cytotoxicity is attributed to a soluble aSN oligomeric species that permeabilizes membranes significantly more than monomers and fibrils. asn 1 Approved Answer. Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic index. Webwhat is the effect of asn oligomerization on luvs This is a single blog caption. While Mic10 is part of a large hetero-oligomeric complex, it has been proposed that the protein itself might form homo-oligomers in the IM (Harner et al., 2011).Mic10 has two highly conserved elongated GxxxG motifs in its two transmembrane domains (Figure (Select all that apply.) Some biologically important oligomers are macromolecules like proteins or nucleic acids; for instance, hemoglobin is a protein tetramer. What is the effect of oligomerization on LUVs? Asn, Gln, Ser, Ala, Gly, Phe, Leu, Met and Trp analogs were indiscriminate and populated two-stranded and three-stranded states. The Nutrizion > Blog Classic > Uncategorized > what is the effect of asn oligomerization on luvs. Biochim Biophys Acta Gen Subj. Mary Ann Liebert, Inc., publishers 140 Huguenot Street, 3rd Floor New Rochelle, NY 10801 USA. Libraries were combined in 8-plex using different barcodes and subjected to 50-base single-end sequencing on a HiSeq 2500 instrument (Illumina). Disclaimer. Report at a scam and speak to a recovery consultant for free. As a next step, the transcriptomic profiling results need to be supported by thorough biochemical and mechanistic studies [29]. Kornienko AE, Guenzl PM, Barlow DP, Pauler FM. 35,000 LECs per well were seeded into a 12-well plate and cultured overnight. Webpurpose of DNA template required as basis of new DNA sequence amplification; perform DNA isolation to extract DNA from cells problem with contamination in PCR presence of To explore the functional role of lncRNAs in LECs or BECs, we performed antisense oligonucleotide-mediated knockdown (ASOKD) of four lncRNA candidates, previously identified as LEC- or BEC-specific lncRNAs, followed by CAGE-Seq [18]. The plate was incubated for 1h at 37C. what is the effect of asn oligomerization on luvs Specificity of RNAi, LNA and CRISPRi as loss-of-function methods in transcriptional analysis. Kim D, Pertea G, Trapnell C, Pimentel H, Kelley R, Salzberg SL. WebAntisense oligonucleotide (ASOs) are small-sized single-stranded nucleic acids and offer some advantage over siRNAs in terms of targeting both nuclear and cytoplasmic located Report at a scam and speak to a recovery consultant for free. 2020;11:787. Oliver G, Kipnis J, Randolph GJ, Harvey NL. Crone NSA, van Hilten N, van der Ham A, Risselada HJ, Kros A, Boyle AL. Our results showed a thermodynamic stability order (in order of decreasing stability) of: Leu, Met, Ile, Tyr, Phe, Val, Gln, Ala, Trp, Asn, His, Thr, Lys, Ser, Asp, Glu, Arg, Orn, and Gly. LECs and BECs were first transfected in duplicates with eight ASOs independently (negative control A and B and three ASO per lncRNA target; Additionalfile1). Schmitz SU, Grote P, Herrmann BG. Second, 4-methylumbelliferyl heptanoate (MUH) proliferation assay showed that negative control B transfection significantly inhibited the proliferation of LECs (Fig. This vast functional repertoire of lncRNAs has led to the novel idea of RNA as a central molecule in the regulation of gene functions. WebWhat is the effect of aSN oligomerization on LUVs? Arts and Humanities. While all three animal aSNs showed significantly weakened fibrillation, elephant aSN formed much more oligomer, and pig aSN much less, than human aSN did. 2015;26(9-10):391402. contributed to the quantification of CAGE-Seq data and provided comments to the manuscript. https://doi.org/10.1016/j.bbagen.2018.01.002. Finally, measuring cellular uptake through microscopy or testing the target cleavage by biochemical techniques (such as 5/3-RACE) is an additional layer of control experiments that can support the proper localization and gene knockdown of the target of interest [30, 37]. 2010;1(6):44752. Languages. https://doi.org/10.1093/nar/gkm226. Google Scholar. Yesterday I was flying Majestic Dash-84 LFPO-EDTT, the weather at EDDT was bad (note that there should be no possibility of hurricanes near Berlin, a bad weather there has to have a limit as to how bad it can be). 1999 Jan 15;285(2):785-803. doi: 10.1006/jmbi.1998.2284. Solved How does EGCG prevent aSN toxicity? a) By binding to https://doi.org/10.1042/BJ20130323. . Compared to the negative control, what is the effect of is that oligomerization is (chemistry) the formation of an oligomer from a monomer while polymerization is (chemistry) the chemical process, normally with the aid of a catalyst, to form a polymer by bonding together multiple identical units (monomers). Further, GO enrichment analysis of the DE genes common between negative control A and B showed, in both cell types, an enrichment for biological processes associated mainly with responding to external factors (Fig. HHS Vulnerability Disclosure, Help CAS https://doi.org/10.1038/s41556-019-0311-8. -Synucleins from Animal Species Show Low Fibrillation - PubMed Orientation, positional, additivity, and oligomerization-state effects of interhelical ion pairs in alpha-helical coiled-coils. [3] Telomerization is an oligomerization carried out under conditions that result in chain transfer, limiting the size of the oligomers.
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